Evaluation of plasma homocysteine level in ischemic stroke patients according to migraine history

Authors

  • Mazyar Hasanzadeh Kyani
  • Mehdi Maghbooli
  • Mehran Yoosefi
Abstract:

Background: As yet migraine has been established as one of the risk factors for ischemic stroke. Some of the factors have been assessed for the explanation of this relation. Hyperhomocysteinemia is seen partly both in stroke and in migraine. This study was conducted to determine the mean plasma levels of homocysteine in ischemic stroke patients on the basis of migraine history.Methods: This cross-sectional study comprised of 100 consecutive patients who were admitted in Neurology Ward of Zanjan Vali Asr Hospital with definite ischemic stroke diagnosis (during 2008). In each patient, the age, gender, history and type of migraine, the time interval from the last migraine attack to stroke and fasting total plasma homocysteine level were ascertained. Results: The mean level of total plasma homocysteine was 26.6±9.6 µmol/l. Fourteen out of 100 patients admitted with ischemic stroke had a history of migraine. The mean of plasma homocysteine did not differ significantly between the two groups with and without migraine (29.93±14.45 versus 26.1±8.6µmol/l, p=0.165). Overall, 83% of patients had hyperhomocysteinemia, wherea,s this state was observed for 92.9% of migrainous and 81.4% of nonmigrainous subjects. The proportion of hyperhomocysteinemia was not different between these two groups (p=0.29). There were not any significant differences regarding the mean plasma levels of homocysteine regarding age, sex, migraine type, the time interval from the last migraine attack to stroke and vascular territory of stroke between these two groups.Conclusion: The results show that the mean levels of homocysteine in ischemic stroke patients who had migraine was similar to those without migraine.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

evaluation of plasma homocysteine level in ischemic stroke patients according to migraine history

background: as yet migraine has been established as one of the risk factors for ischemic stroke. some of the factors have been assessed for the explanation of this relation. hyperhomocysteinemia is seen partly both in stroke and in migraine. this study was conducted to determine the mean plasma levels of homocysteine in ischemic stroke patients on the basis of migraine history.methods: this cro...

full text

Evaluation of Homocysteine Level as a Risk Factor among Patients with Ischemic Stroke and Its Subtypes

Background: Epidemiological research has shown that increased total homocysteine (tHcy) levels are associated with an increased risk of thromboembolic disease; however, controversy still exists over which subtype of stroke is allied to hyperhomocysteinemia. This study aimed to investigate whether elevated tHcy is an independent risk factor for ischemic stroke and to compare tHcy levels in patie...

full text

The Plasma Level of Parathormon and Homocysteine in Migraine Patients; Another Aspect on Migraine-stroke Associaton

SEFER VAROL1, ESREF AKIL1, MUHARREM YUNCE2, BRAHIM KAPLAN2, HASAN HÜSEYIN ÖZDEMIR1, DEMET ARSLAN1, AHMET YILMAZ3, MEHMET HALIS TANRIVERDI3 1Department of Neurology, Faculty of Medicine, Dicle University Hospital, Diyarbakir 2Department of Medical Biochemistry, Faculty of Medicine, Dicle University, Diyarbakir 3Department of Family Medicine, Faculty of Medicine, Dicle University, Diyarbakir, Turkey

full text

Plasma homocysteine level and the course of ischemic stroke.

Increased level of homocysteine (Hcy) in blood seems to influence negatively the course of ischemic stroke (IS), the possible mechanism of this action could be acceleration of oxidative stress. The aim of this study is to assess the influence of Hcy level in patients with IS on the prognosis 3 months after the stroke onset. 75 patients aged 68.27 +/- 12.62 years, with the diagnosis of first eve...

full text

evaluation of homocysteine level as a risk factor among patients with ischemic stroke and its subtypes

background: epidemiological research has shown that increased total homocysteine (thcy) levels are associated with an increased risk of thromboembolic disease; however, controversy still exists over which subtype of stroke is allied to hyperhomocysteinemia. this study aimed to investigate whether elevated thcy is an independent risk factor for ischemic stroke and to compare thcy levels in patie...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 1  issue None

pages  63- 66

publication date 2010-01

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023